[Sean Roe]

Yes, think of the differences in programs relating to timing advance.
The higher the fuel octane, the earlier you can / should light the cylinder and the more power it will make.
Run the most advance you can without pinging / detonation. You don't have to (shouldn't) rely on your ears. Reading the spark plugs for signs of detonation is easy enough (use a magnifying glass). Look for small spots of "pepper" or little silver beads on the insulator.
You can probably find pictures online also.
We employ several methods of verification during the tuning process used to create the programs we're sending out to everyone.

Regards,
Sean